- Does Combining Zoloft With Alcohol Make Their Symptoms Worse?
QUESTION:
Dear Doctor, I am married to a woman whom I believe has either BPD or another personality disorder. She is also an alcoholic, and although she knows she is, she seems to have no desire to help herself. I see the depression start to set in for a few weeks at first, sometimes lasting several months. Well, she was hit by a car crossing the street and saw a neurologist whom prescribed Zoloft and Amitryptilline. When she starts to get depressed she will start to drink as well. Then I am to blame for all that is wrong in her life. I have been stabbed and burned with cigarettes by her when she drinks. I have seen her do some really self-destructive things as well, including suicide attempts and promiscuous behavior and plain hatred towards me. Does the combination of Zoloft and alcohol cause an even more severe depression?
ANSWER:
It’s more likely the alcohol is making the BPD worse and interfering with Zoloft’s effectiveness.