IS PROZAC WEAKENING? I FEEL BAD. 
Ask The Doctor Dr. Leland Heller Biological Unhappiness 
IS PROZAC WEAKENING? I FEEL BAD. 
Question: I have been on Prozac for 2 years and it doesn’t seem to be as effective as it once was. Is there a certain “life span” of this drug? All I want to do is sleep and hibernate!! It’s miserable. Dr. Heller’s Answer: There are usually two reasons for this phenomenon:
- 1) The BPD (Borderline Personality Disorder) with the development of chronic Dysphoria (anxiety, rage, depression and despair). This will usually go away within three hours with the addition of Tegretol 200mg.2) Prozac raises serotonin. Some people get a relative deficiency state with too low dopamine and noradrenaline. People who experience this feel blah and have a lack of interest in virtually anything. This is resolved with the addition of Wellbutrin, and usually goes away within two weeks. The Wellbutrin is rarely needed for more than 6-8 weeks.
In my opinion, Prozac is necessary for two conditions: the borderline disorder and a genetic depression I describe in “Biological Unhappiness” as “fractured enjoyment.” The cartoon characters Eeyore and Charlie Brown describe this phenomenon well. If neither diagnosis is present, switching to an alternative antidepressant such as Effexor, Wellbutrin or Remeron may be a good choice. 
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